Delivering the most up-to-date information available in a rich, engaging presentation, Medical Physiology: Principles for Clinical Medicine, 6th Edition, instills a complete understanding of physiology essential to effective clinical practice. This robust text not only details how the human body reacts to internal and external changes but also provides a deep understanding of how physiologic systems coordinate to maintain optimal health, as well as the involvement of altered functions in disease processes. Extensively updated throughout and fully aligned with today's medical curriculum, the 6th Edition emphasizes the physiologic principles key to understanding human function, places them in their fundamental context in clinical medicine, and provides opportunities for student self-directed and team-based learning through case studies, clinical application exercises, and board-style review questions.